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Gene/Cell Therapy Approaches for Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome

Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) syndrome is a rare autoimmune disease due to mutations in the gene encoding for Forkhead box P3 (FOXP3), a transcription factor fundamental for the function of thymus-derived (t) regulatory T (Treg) cells. The dysfunction of Treg...

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Detalles Bibliográficos
Autores principales: Passerini, Laura, Santoni de Sio, Francesca R., Porteus, Matthew H., Bacchetta, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443799/
https://www.ncbi.nlm.nih.gov/pubmed/25274247
http://dx.doi.org/10.2174/1566523214666141001123828