Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP

The E3 ubiquitin ligase CHIP is involved in protein triage, serving as a co-chaperone for refolding as well as catalyzing ubiquitination of substrates. CHIP functions with both the stress induced Hsp70 and constitutive Hsc70 chaperones, and also plays a role in maintaining their balance in the cell....

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Detalles Bibliográficos
Autores principales: Soss, Sarah E., Rose, Kristie L., Hill, Salisha, Jouan, Sophie, Chazin, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444009/
https://www.ncbi.nlm.nih.gov/pubmed/26010904
http://dx.doi.org/10.1371/journal.pone.0128240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444009/
https://www.ncbi.nlm.nih.gov/pubmed/26010904
http://dx.doi.org/10.1371/journal.pone.0128240

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