HIV-1 Treated Patients with Undetectable Viral Loads have Lower Levels of Innate Immune Responses via Cytosolic DNA Sensing Systems Compared with Healthy Uninfected Controls

OBJECTIVES: After DNA or RNA virus infection, cytosolic foreign DNA or RNA derived from the infecting viruses is recognized by intracellular pathogen recognition receptors (PRRs) and induces activation of the innate immune system. Transfection of DNA has been used as an experimental model for DNA vi...

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Detalles Bibliográficos
Autores principales: Swaminathan, Sanjay, Sui, Hongyan, Adelsberger, Joseph W, Chen, Qian, Sneller, Michael, Migueles, Stephen A, Kottilil, Shyamasundaran, Ober, Alexander, Jones, Sara, Rehm, Catherine A, Lane, H Clifford, Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444065/
https://www.ncbi.nlm.nih.gov/pubmed/26023356
http://dx.doi.org/10.4172/2155-6113.1000315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444065/
https://www.ncbi.nlm.nih.gov/pubmed/26023356
http://dx.doi.org/10.4172/2155-6113.1000315

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