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Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit
The anti-tumor effects of chemotherapy and radiation are thought to be mediated by triggering G(1)/S or G(2)/M cell cycle checkpoints, while spindle poisons, such as paclitaxel, block metaphase exit by initiating the spindle assembly checkpoint. In contrast, we have found that 150 kilohertz (kHz) al...
Autores principales: | Gera, Nidhi, Yang, Aaron, Holtzman, Talia S., Lee, Sze Xian, Wong, Eric T., Swanson, Kenneth D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444126/ https://www.ncbi.nlm.nih.gov/pubmed/26010837 http://dx.doi.org/10.1371/journal.pone.0125269 |
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