Cell extrinsic alterations in splenic B cell maturation in Flt3-ligand knockout mice

B lymphopoiesis in bone marrow (BM) is critical for maintaining a diverse peripheral B cell pool to fight infection and establish lifelong immunity. The generation of immature B cells is reduced in Flt3-ligand (FL-/-) mice leading to deficiencies in splenic B cells. Here, we sought to understand the...

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Detalles Bibliográficos
Autores principales: Dolence, Joseph J, Gwin, Kimberly A, Shapiro, Mariya B, Hsu, Fan-Chi, Shapiro, Virginia S, Medina, Kay L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444153/
https://www.ncbi.nlm.nih.gov/pubmed/26029370
http://dx.doi.org/10.1002/iid3.54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444153/
https://www.ncbi.nlm.nih.gov/pubmed/26029370
http://dx.doi.org/10.1002/iid3.54

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