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Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats

BACKGROUND: There is growing interest in sex differences and RAS components. However, whether gender influences cardiac angiotensin I-converting enzyme (ACE) and angiotensin-converting enzyme 2 (ACE2) activity is still unknown. In the present work, we determined the relationship between ACE and ACE2...

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Detalles Bibliográficos
Autores principales: Dalpiaz, P. L. M., Lamas, A. Z., Caliman, I. F., Ribeiro, R. F., Abreu, G. R., Moyses, M. R., Andrade, T. U., Gouvea, S. A., Alves, M. F., Carmona, A. K., Bissoli, N. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444272/
https://www.ncbi.nlm.nih.gov/pubmed/26010093
http://dx.doi.org/10.1371/journal.pone.0127515