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Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

A fundamental challenge for developing an effective and safe HIV-1 vaccine is to identify vaccine immunogens that can initiate and maintain immune responses leading to elicitation of broadly neutralizing HIV-1 antibodies (bnAbs) through complex maturation pathways. We have previously found that HIV-...

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Detalles Bibliográficos
Autores principales: Yang, Zheng, Li, Jingjing, Liu, Qingsheng, Yuan, Tingting, Zhang, Yanyu, Chen, Li-Qing, Lou, Qi, Sun, Zehua, Ying, Huazhong, Xu, Jianqing, Dimitrov, Dimiter S., Zhang, Mei-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444298/
https://www.ncbi.nlm.nih.gov/pubmed/26010511
http://dx.doi.org/10.1371/journal.pone.0126428