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Structural Basis of pH Dependence of Neoculin, a Sweet Taste-Modifying Protein

Among proteins utilized as sweeteners, neoculin and miraculin are taste-modifying proteins that exhibit pH-dependent sweetness. Several experiments on neoculin have shown that His11 of neoculin is responsible for pH dependence. We investigated the molecular mechanism of the pH dependence of neoculin...

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Detalles Bibliográficos
Autores principales: Ohkubo, Takayuki, Tamiya, Minoru, Abe, Keiko, Ishiguro, Masaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444330/
https://www.ncbi.nlm.nih.gov/pubmed/26010443
http://dx.doi.org/10.1371/journal.pone.0126921