The Fitness Consequences of Aneuploidy Are Driven by Condition-Dependent Gene Effects

Aneuploidy is a hallmark of tumor cells, and yet the precise relationship between aneuploidy and a cell’s proliferative ability, or cellular fitness, has remained elusive. In this study, we have combined a detailed analysis of aneuploid clones isolated from laboratory-evolved populations of Saccharo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sunshine, Anna B., Payen, Celia, Ong, Giang T., Liachko, Ivan, Tan, Kean Ming, Dunham, Maitreya J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444335/
https://www.ncbi.nlm.nih.gov/pubmed/26011532
http://dx.doi.org/10.1371/journal.pbio.1002155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444335/
https://www.ncbi.nlm.nih.gov/pubmed/26011532
http://dx.doi.org/10.1371/journal.pbio.1002155

Ejemplares similares