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Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial

BACKGROUND: A randomized multicenter phase II trial was conducted to assess the sequential treatment strategy using FOLFIRI.3 and gemcitabine alternately (Arm 2) compared to gemcitabine alone (Arm 1) in patients with metastatic non pre-treated pancreatic adenocarcinoma. The primary endpoint was the...

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Detalles Bibliográficos
Autores principales: Anota, Amélie, Mouillet, Guillaume, Trouilloud, Isabelle, Dupont-Gossart, Anne-Claire, Artru, Pascal, Lecomte, Thierry, Zaanan, Aziz, Gauthier, Mélanie, Fein, Francine, Dubreuil, Olivier, Paget-Bailly, Sophie, Taieb, Julien, Bonnetain, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444351/
https://www.ncbi.nlm.nih.gov/pubmed/26010884
http://dx.doi.org/10.1371/journal.pone.0125350