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Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial
BACKGROUND: A randomized multicenter phase II trial was conducted to assess the sequential treatment strategy using FOLFIRI.3 and gemcitabine alternately (Arm 2) compared to gemcitabine alone (Arm 1) in patients with metastatic non pre-treated pancreatic adenocarcinoma. The primary endpoint was the...
Autores principales: | Anota, Amélie, Mouillet, Guillaume, Trouilloud, Isabelle, Dupont-Gossart, Anne-Claire, Artru, Pascal, Lecomte, Thierry, Zaanan, Aziz, Gauthier, Mélanie, Fein, Francine, Dubreuil, Olivier, Paget-Bailly, Sophie, Taieb, Julien, Bonnetain, Franck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444351/ https://www.ncbi.nlm.nih.gov/pubmed/26010884 http://dx.doi.org/10.1371/journal.pone.0125350 |
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