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Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B
Negative elongation factor (NELF), a four-subunit protein complex in metazoan, plays an important role in regulating promoter-proximal pausing of RNA polymerase II (RNAPII). Genetic studies demonstrate that the B subunit of mouse NELF (NELF-B) is critical for embryonic development and homeostasis in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444357/ https://www.ncbi.nlm.nih.gov/pubmed/26010750 http://dx.doi.org/10.1371/journal.pone.0127422 |