CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis

CD47 is a widely expressed receptor that regulates immunity by engaging its counter-receptor SIRPα on phagocytes and its secreted ligand thrombospondin-1. Mice lacking CD47 can exhibit enhanced or impaired host responses to bacterial pathogens, but its role in fungal immunity has not been examined....

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Detalles Bibliográficos
Autores principales: Navarathna, Dhammika H. M. L. P., Stein, Erica V., Lessey-Morillon, Elizabeth C., Nayak, Debasis, Martin-Manso, Gema, Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444371/
https://www.ncbi.nlm.nih.gov/pubmed/26010544
http://dx.doi.org/10.1371/journal.pone.0128220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444371/
https://www.ncbi.nlm.nih.gov/pubmed/26010544
http://dx.doi.org/10.1371/journal.pone.0128220

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