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CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis
CD47 is a widely expressed receptor that regulates immunity by engaging its counter-receptor SIRPα on phagocytes and its secreted ligand thrombospondin-1. Mice lacking CD47 can exhibit enhanced or impaired host responses to bacterial pathogens, but its role in fungal immunity has not been examined....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444371/ https://www.ncbi.nlm.nih.gov/pubmed/26010544 http://dx.doi.org/10.1371/journal.pone.0128220 |