Sodium bicarbonate protects uranium-induced acute nephrotoxicity through uranium-decorporation by urinary alkalinization in rats

To evaluate the effectiveness of sodium bicarbonate (SB) in removing uranium and protecting animals from uranium toxicity, we intramuscularly administered 1 mg/kg of uranyl nitrate to 8-wk-old male SD rats, and 20 min after administration of uranyl nitrate, the animals were given a single oral admin...

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Detalles Bibliográficos
Autores principales: Ohmachi, Yasushi, Imamura, Tomomi, Ikeda, Mizuyo, Shishikura, Eriko, Kim, Eunjoo, Kurihara, Osamu, Sakai, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444504/
https://www.ncbi.nlm.nih.gov/pubmed/26028815
http://dx.doi.org/10.1293/tox.2014-0041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444504/
https://www.ncbi.nlm.nih.gov/pubmed/26028815
http://dx.doi.org/10.1293/tox.2014-0041

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