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Sodium bicarbonate protects uranium-induced acute nephrotoxicity through uranium-decorporation by urinary alkalinization in rats
To evaluate the effectiveness of sodium bicarbonate (SB) in removing uranium and protecting animals from uranium toxicity, we intramuscularly administered 1 mg/kg of uranyl nitrate to 8-wk-old male SD rats, and 20 min after administration of uranyl nitrate, the animals were given a single oral admin...
Autores principales: | Ohmachi, Yasushi, Imamura, Tomomi, Ikeda, Mizuyo, Shishikura, Eriko, Kim, Eunjoo, Kurihara, Osamu, Sakai, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444504/ https://www.ncbi.nlm.nih.gov/pubmed/26028815 http://dx.doi.org/10.1293/tox.2014-0041 |
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