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Obstructive nephropathy induced with DL-potassium hydrogen tartrate in F344 rats

We experienced obstructive nephropathy in F344 rats treated with DL-potassium hydrogen tartrate (PHT) in a 13-week oral repeated dose toxicity study. Six-week-old male and female F344/DuCrj rats were fed a diet containing up to 2.0% PHT for 13 weeks. Microscopical findings including irregular dilati...

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Detalles Bibliográficos
Autores principales: Inoue, Kaoru, Morikawa, Tomomi, Takahashi, Miwa, Yoshida, Midori, Ogawa, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444507/
https://www.ncbi.nlm.nih.gov/pubmed/26028818
http://dx.doi.org/10.1293/tox.2014-0058