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Obstructive nephropathy induced with DL-potassium hydrogen tartrate in F344 rats
We experienced obstructive nephropathy in F344 rats treated with DL-potassium hydrogen tartrate (PHT) in a 13-week oral repeated dose toxicity study. Six-week-old male and female F344/DuCrj rats were fed a diet containing up to 2.0% PHT for 13 weeks. Microscopical findings including irregular dilati...
Autores principales: | Inoue, Kaoru, Morikawa, Tomomi, Takahashi, Miwa, Yoshida, Midori, Ogawa, Kumiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444507/ https://www.ncbi.nlm.nih.gov/pubmed/26028818 http://dx.doi.org/10.1293/tox.2014-0058 |
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