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A Redox-Sensitive Micelle-Like Nanoparticle Self-Assembled from Amphiphilic Adriamycin-Human Serum Albumin Conjugates for Tumor Targeted Therapy

The application of chemotherapeutic drug adriamycin (ADR) in cancer therapy is limited by its side effects like high toxicity and insolubility. Nanomedicine offers new hope for overcoming the shortcomings. But how to increase in vivo stability and to control intracellular drug release is a key issue...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Chen, Feng, Zhao, Mengxin, Zhu, Xiandi, Ke, Changhong, Yu, Jiangming, Yan, Zhiqiang, Zhang, Fulei, Sun, Yun, Chen, Di, Jiang, Cheng, Zhao, Xianxian, Gao, Yong, Guo, Shangjing, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444569/
https://www.ncbi.nlm.nih.gov/pubmed/26075280
http://dx.doi.org/10.1155/2015/987404