Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors

Animals prenatally exposed to valproic acid (VPA), an antiepileptic agent, have been used as a model for autism spectrum disorders (ASDs). Previous studies have identified enhanced NMDA receptor (NMDAR) function in the brain of VPA rats, and demonstrated that pharmacological suppression of NMDAR fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Jaeseung, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444740/
https://www.ncbi.nlm.nih.gov/pubmed/26074764
http://dx.doi.org/10.3389/fnmol.2015.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444740/
https://www.ncbi.nlm.nih.gov/pubmed/26074764
http://dx.doi.org/10.3389/fnmol.2015.00017

Ejemplares similares