Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues are largely uncharted. We analyzed 6,260 human piRNA transcriptomes derived from non-malignant and tumour tissues from 11 organs. We...

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Detalles Bibliográficos
Autores principales: Martinez, Victor D., Vucic, Emily A., Thu, Kelsie L., Hubaux, Roland, Enfield, Katey S.S., Pikor, Larissa A., Becker-Santos, Daiana D., Brown, Carolyn J., Lam, Stephen, Lam, Wan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444957/
https://www.ncbi.nlm.nih.gov/pubmed/26013764
http://dx.doi.org/10.1038/srep10423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444957/
https://www.ncbi.nlm.nih.gov/pubmed/26013764
http://dx.doi.org/10.1038/srep10423

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