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High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors
Gene transfer vectors based upon human immunodeficiency virus type 1 (HIV) are widely used in bench research applications and increasingly in clinical investigations, both to introduce novel genes but also to reduce expression of unwanted genes of the host and pathogen. At present, the vast majority...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444993/ https://www.ncbi.nlm.nih.gov/pubmed/26029715 http://dx.doi.org/10.1038/mtm.2015.4 |