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Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho(–/–) mouse
As gene therapies for various forms of retinal degeneration progress toward human clinical trial, it will be essential to have a repertoire of safe and efficient vectors for gene delivery to the target cells. Recombinant adeno-associated virus (AAV) serotype 2/2 has been shown to be well tolerated i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444994/ https://www.ncbi.nlm.nih.gov/pubmed/26029727 http://dx.doi.org/10.1038/mtm.2015.16 |