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Lysophosphatidic acid induces YAP-promoted proliferation of human corneal endothelial cells via PI3K and ROCK pathways

The first two authors contributed equally to this work.Silence of p120-catenin has shown promise in inducing proliferation in human corneal endothelial cells (HCECs), but there is concern regarding off-target effects in potential clinical applications. We aimed to develop ex vivo expansion of HCECs...

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Detalles Bibliográficos
Autores principales: Hsueh, Yi-Jen, Chen, Hung-Chi, Wu, Sung-En, Wang, Tze-Kai, Chen, Jan-Kan, Ma, David Hui-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445000/
https://www.ncbi.nlm.nih.gov/pubmed/26029725
http://dx.doi.org/10.1038/mtm.2015.14