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PIK3CA Amplification Is Common in Left Side-Tubular Adenomas but Uncommon Sessile Serrated Adenomas Exclusively with KRAS Mutation

Colorectal cancer is a heterogeneous disorder than arises via multiple distinct pathways, from tubular adenomas (TAs) and sessile serrated adenomas (SSAs), which are clinically, morphologically, and molecularly different. We examined PIK3CA amplification in colorectal precancerous legions, including...

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Detalles Bibliográficos
Autores principales: Lee, Hyunsu, Lee, Jae-Ho, Kim, Dae-Kwang, Choi, In-Jang, Hwang, Ilseon, Kang, Yu-Na, Kim, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445015/
https://www.ncbi.nlm.nih.gov/pubmed/26019684
http://dx.doi.org/10.7150/ijms.11281