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A transcription and translation-coupled DNA replication system using rolling-circle replication

All living organisms have a genome replication system in which genomic DNA is replicated by a DNA polymerase translated from mRNA transcribed from the genome. The artificial reconstitution of this genome replication system is a great challenge in in vitro synthetic biology. In this study, we attempt...

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Detalles Bibliográficos
Autores principales: Sakatani, Yoshihiro, Ichihashi, Norikazu, Kazuta, Yasuaki, Yomo, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445062/
https://www.ncbi.nlm.nih.gov/pubmed/26013404
http://dx.doi.org/10.1038/srep10404