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A Base-Independent Repair Mechanism for DNA Glycosylase—No Discrimination Within the Active Site
The ubiquitous occurrence of DNA damages renders its repair machinery a crucial requirement for the genomic stability and the survival of living organisms. Deficiencies in DNA repair can lead to carcinogenesis, Alzheimer, or Diabetes II, where increased amounts of oxidized DNA bases have been found...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445063/ https://www.ncbi.nlm.nih.gov/pubmed/26013033 http://dx.doi.org/10.1038/srep10369 |