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A Base-Independent Repair Mechanism for DNA Glycosylase—No Discrimination Within the Active Site

The ubiquitous occurrence of DNA damages renders its repair machinery a crucial requirement for the genomic stability and the survival of living organisms. Deficiencies in DNA repair can lead to carcinogenesis, Alzheimer, or Diabetes II, where increased amounts of oxidized DNA bases have been found...

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Detalles Bibliográficos
Autores principales:	Blank, Iris D., Sadeghian, Keyarash, Ochsenfeld, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445063/ https://www.ncbi.nlm.nih.gov/pubmed/26013033 http://dx.doi.org/10.1038/srep10369

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