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Toxic species in amyloid disorders: Oligomers or mature fibrils

Protein aggregation is the hallmark of several neurodegenerative disorders. These protein aggregation (fibrillization) disorders are also known as amyloid disorders. The mechanism of protein aggregation involves conformation switch of the native protein, oligomer formation leading to protofibrils an...

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Detalles Bibliográficos
Autores principales: Verma, Meenakshi, Vats, Abhishek, Taneja, Vibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445186/
https://www.ncbi.nlm.nih.gov/pubmed/26019408
http://dx.doi.org/10.4103/0972-2327.144284