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Chromosome 17 copy number changes in male breast cancer

BACKGROUND: Overall, HER2-amplified female breast cancer (FBC) is associated with a high grade, an aggressive phenotype and a poor prognosis. In male breast cancer (MBC) amplification of HER2, located on chromosome 17, occurs at a lower frequency than in FBC, where it is part of complex rearrangemen...

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Detalles Bibliográficos
Autores principales: Lacle, Miangela M., Moelans, Cathy B., Kornegoor, Robert, van der Pol, Carmen, Witkamp, Arjen J., van der Wall, Elsken, Rueschoff, Josef, Buerger, Horst, van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445249/
https://www.ncbi.nlm.nih.gov/pubmed/25906114
http://dx.doi.org/10.1007/s13402-015-0227-7