Preclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP)

BACKGROUND: The clinical development of advanced therapy medicinal products (ATMPs), a new class of drugs, requires initial safety studies that deviate from standard non-clinical safety protocols. The study provides a strategy to address the safety aspects of biodistribution and tumorigenicity of AT...

Descripción completa

Detalles Bibliográficos
Autores principales: Zscharnack, Matthias, Krause, Christoph, Aust, Gabriela, Thümmler, Christian, Peinemann, Frank, Keller, Thomas, Smink, Jeske J., Holland, Heidrun, Somerson, Jeremy S., Knauer, Jens, Schulz, Ronny M., Lehmann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445304/
https://www.ncbi.nlm.nih.gov/pubmed/25990108
http://dx.doi.org/10.1186/s12967-015-0517-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445304/
https://www.ncbi.nlm.nih.gov/pubmed/25990108
http://dx.doi.org/10.1186/s12967-015-0517-x

Ejemplares similares