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Unbalanced Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinases Ratios Predict Hemorrhagic Transformation of Lesion in Ischemic Stroke Patients Treated with Thrombolysis: Results from the MAGIC Study

BACKGROUND: Experimentally, metalloproteinases (MMPs) play a detrimental role related to the severity of ischemic brain lesions. Both MMPs activity and function in tissues reflect the balance between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We aimed to evaluate the role of MMPs/TIMP...

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Detalles Bibliográficos
Autores principales: Piccardi, Benedetta, Palumbo, Vanessa, Nesi, Mascia, Nencini, Patrizia, Gori, Anna Maria, Giusti, Betti, Pracucci, Giovanni, Tonelli, Paolina, Innocenti, Eleonora, Sereni, Alice, Sticchi, Elena, Toni, Danilo, Bovi, Paolo, Guidotti, Mario, Tola, Maria Rosaria, Consoli, Domenico, Micieli, Giuseppe, Tassi, Rossana, Orlandi, Giovanni, Perini, Francesco, Marcello, Norina, Nucera, Antonia, Massaro, Francesca, DeLodovici, Maria Luisa, Bono, Giorgio, Sessa, Maria, Abbate, Rosanna, Inzitari, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445323/
https://www.ncbi.nlm.nih.gov/pubmed/26074872
http://dx.doi.org/10.3389/fneur.2015.00121