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Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates

Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide. Chikungunya virus is an emerging disease problem that is b...

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Detalles Bibliográficos
Autores principales: Saisawang, Chonticha, Sillapee, Pornpan, Sinsirimongkol, Kwanhathai, Ubol, Sukathida, Smith, Duncan R., Ketterman, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445351/
https://www.ncbi.nlm.nih.gov/pubmed/26182358
http://dx.doi.org/10.1042/BSR20150086