Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio

Insulinomas cause neuroglycopenic symptoms, permanent neurological damage and even death. Current available therapies cannot satisfactorily treat malignant insulinomas and some benign insulinomas. The promising phototherapeutic results and harmless side effects of hypericin in some cancer treatments...

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Detalles Bibliográficos
Autores principales: Yi, Jingwen, Yang, Xiaoguang, Zheng, Lihua, Yang, Guang, Sun, Luguo, Bao, Yongli, Wu, Yin, Huang, Yanxin, Yu, Chunlei, Yang, Shao-Nian, Li, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445353/
https://www.ncbi.nlm.nih.gov/pubmed/26182357
http://dx.doi.org/10.1042/BSR20150028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445353/
https://www.ncbi.nlm.nih.gov/pubmed/26182357
http://dx.doi.org/10.1042/BSR20150028

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