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An old Twist in HLA-A: CDR3α Hook up at an R65-joint
T-cell ontogeny optimizes the α/β T-cell receptor (TCR) repertoire for recognition of major histocompatibility complex (MHC) class-I/II genetic polymorphism, and co-evolution of TCR germline V-gene segments and the MHC must entail somatic diversity generated in the third complimentary determining re...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445401/ https://www.ncbi.nlm.nih.gov/pubmed/26074926 http://dx.doi.org/10.3389/fimmu.2015.00268 |