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An old Twist in HLA-A: CDR3α Hook up at an R65-joint

T-cell ontogeny optimizes the α/β T-cell receptor (TCR) repertoire for recognition of major histocompatibility complex (MHC) class-I/II genetic polymorphism, and co-evolution of TCR germline V-gene segments and the MHC must entail somatic diversity generated in the third complimentary determining re...

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Detalles Bibliográficos
Autor principal:	Murray, Joseph S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445401/ https://www.ncbi.nlm.nih.gov/pubmed/26074926 http://dx.doi.org/10.3389/fimmu.2015.00268

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