Approaches to Identifying Synthetic Lethal Interactions in Cancer

Targeting synthetic lethal interactions is a promising new therapeutic approach to exploit specific changes that occur within cancer cells. Multiple approaches to investigate these interactions have been developed and successfully implemented, including chemical, siRNA, shRNA, and CRISPR library scr...

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Detalles Bibliográficos
Autores principales: Thompson, Jordan M., Nguyen, Quy H., Singh, Manpreet, Razorenova, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445436/
https://www.ncbi.nlm.nih.gov/pubmed/26029013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445436/
https://www.ncbi.nlm.nih.gov/pubmed/26029013

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