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Piezo1 ion channel pore properties are dictated by C-terminal region

Piezo1 and Piezo2 encode mechanically activated cation channels that function as mechanotransducers involved in vascular system development and touch sensing, respectively. Structural features of Piezos remain unknown. Mouse Piezo1 is bioinformatically predicted to have 30–40 transmembrane (TM) doma...

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Detalles Bibliográficos
Autores principales: Coste, Bertrand, Murthy, Swetha E., Mathur, Jayanti, Schmidt, Manuela, Mechioukhi, Yasmine, Delmas, Patrick, Patapoutian, Ardem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445471/
https://www.ncbi.nlm.nih.gov/pubmed/26008989
http://dx.doi.org/10.1038/ncomms8223