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Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation
BACKGROUND: Small non-coding RNA molecules (miRNAs) play a pivotal role in regulating gene expression in development. miRNAs regulate key processes at the cellular level and thereby influence organismal and tissue development including kidney morphogenesis. A miRNA molecule is initially synthesized...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445526/ https://www.ncbi.nlm.nih.gov/pubmed/25881298 http://dx.doi.org/10.1186/s12882-015-0053-1 |