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Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition

The present study investigated the effect of silibinin, the principal potential anti-inflammatory flavonoid contained in silymarin, a mixture of flavonolignans extracted from Silybum marianum seeds, on palmitate-induced insulin resistance in C2C12 myotubes and its potential molecular mechanisms. Sil...

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Detalles Bibliográficos
Autores principales: Li, H.B., Yang, Y.R.Y., Mo, Z.J., Ding, Y., Jiang, W.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445668/
https://www.ncbi.nlm.nih.gov/pubmed/25760026
http://dx.doi.org/10.1590/1414-431X20144238