Cargando…
Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition
The present study investigated the effect of silibinin, the principal potential anti-inflammatory flavonoid contained in silymarin, a mixture of flavonolignans extracted from Silybum marianum seeds, on palmitate-induced insulin resistance in C2C12 myotubes and its potential molecular mechanisms. Sil...
Autores principales: | Li, H.B., Yang, Y.R.Y., Mo, Z.J., Ding, Y., Jiang, W.J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445668/ https://www.ncbi.nlm.nih.gov/pubmed/25760026 http://dx.doi.org/10.1590/1414-431X20144238 |
Ejemplares similares
-
Quercetin postconditioning attenuates myocardial
ischemia/reperfusion injury in rats through the PI3K/Akt pathway
por: Wang, Y., et al.
Publicado: (2013) -
Effect and the probable mechanisms of silibinin in
regulating insulin resistance in the liver of rats with non-alcoholic fatty
liver
por: Yao, Jiayin, et al.
Publicado: (2013) -
Association between the c.910A>G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population
por: Chen, X.Q., et al.
Publicado: (2013) -
Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes
por: Yang, Ming, et al.
Publicado: (2013) -
Antioxidant effect of mogrosides against oxidative stress
induced by palmitic acid in mouse insulinoma NIT-1 cells
por: Xu, Q., et al.
Publicado: (2013)