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Improved drug therapy: triangulating phenomics with genomics and metabolomics

Embracing the complexity of biological systems has a greater likelihood to improve prediction of clinical drug response. Here we discuss limitations of a singular focus on genomics, epigenomics, proteomics, transcriptomics, metabolomics, or phenomics—highlighting the strengths and weaknesses of each...

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Detalles Bibliográficos
Autores principales: Monte, Andrew A, Brocker, Chad, Nebert, Daniel W, Gonzalez, Frank J, Thompson, David C, Vasiliou, Vasilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445687/
https://www.ncbi.nlm.nih.gov/pubmed/25181945
http://dx.doi.org/10.1186/s40246-014-0016-9