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The relative contribution of common and rare genetic variants to ADHD

Attention deficit hyperactivity disorder (ADHD) is highly heritable. Genome-wide molecular studies show an increased burden of large, rare copy-number variants (CNVs) in children with ADHD compared with controls. Recent polygenic risk score analyses have also shown that en masse common variants are...

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Detalles Bibliográficos
Autores principales: Martin, J, O'Donovan, M C, Thapar, A, Langley, K, Williams, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445754/
https://www.ncbi.nlm.nih.gov/pubmed/25668434
http://dx.doi.org/10.1038/tp.2015.5