Evaluation of the effect of tofacitinib on measured glomerular filtration rate in patients with active rheumatoid arthritis: results from a randomised controlled trial

INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). During the clinical development programme, increases in mean serum creatinine (SCr) of approximately 0.07 mg/dL and 0.08 mg/dL were observed which plateaued early. This study assessed changes...

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Detalles Bibliográficos
Autores principales: Kremer, Joel M, Kivitz, Alan J, Simon-Campos, Jesus A, Nasonov, Evgeny L, Tony, Hans-Peter, Lee, Soo-Kon, Vlahos, Bonnie, Hammond, Constance, Bukowski, Jack, Li, Huihua, Schulman, Seth L, Raber, Susan, Zuckerman, Andrea, Isaacs, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445792/
https://www.ncbi.nlm.nih.gov/pubmed/25889308
http://dx.doi.org/10.1186/s13075-015-0612-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445792/
https://www.ncbi.nlm.nih.gov/pubmed/25889308
http://dx.doi.org/10.1186/s13075-015-0612-7

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