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Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy

We have developed a theranostic nanoparticle, ie, cet-PEG-dexSPIONs, by conjugation of the anti-epidermal growth factor receptor (EGFR) monoclonal antibody, cetuximab, to dextran-coated superparamagnetic iron oxide nanoparticles (SPIONs) via periodate oxidation. Approximately 31 antibody molecules w...

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Detalles Bibliográficos
Autores principales: Tseng, Shih-Heng, Chou, Min-Yuan, Chu, I-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445874/
https://www.ncbi.nlm.nih.gov/pubmed/26056447
http://dx.doi.org/10.2147/IJN.S80134