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Super-low Dose Endotoxin Pre-conditioning Exacerbates Sepsis Mortality

Sepsis mortality varies dramatically in individuals of variable immune conditions, with poorly defined mechanisms. This phenomenon complements the hypothesis that innate immunity may adopt rudimentary memory, as demonstrated in vitro with endotoxin priming and tolerance in cultured monocytes. Howeve...

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Detalles Bibliográficos
Autores principales: Chen, Keqiang, Geng, Shuo, Yuan, Ruoxi, Diao, Na, Upchurch, Zachary, Li, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445878/
https://www.ncbi.nlm.nih.gov/pubmed/26029736
http://dx.doi.org/10.1016/j.ebiom.2015.03.001