Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells

The heat shock protein 90 (Hsp90) inhibitor geldanamycin (GA) has been shown to alter endosomal sorting, diverting cargo destined for the recycling pathway into the lysosomal pathway. Here we investigated whether GA also affects the sorting of cargo into the retrograde pathway from endosomes to the...

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Detalles Bibliográficos
Autores principales: Lingelem, Anne Berit Dyve, Hjelseth, Ieva Ailte, Simm, Roger, Torgersen, Maria Lyngaas, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445914/
https://www.ncbi.nlm.nih.gov/pubmed/26017782
http://dx.doi.org/10.1371/journal.pone.0129214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445914/
https://www.ncbi.nlm.nih.gov/pubmed/26017782
http://dx.doi.org/10.1371/journal.pone.0129214

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