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Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
The heat shock protein 90 (Hsp90) inhibitor geldanamycin (GA) has been shown to alter endosomal sorting, diverting cargo destined for the recycling pathway into the lysosomal pathway. Here we investigated whether GA also affects the sorting of cargo into the retrograde pathway from endosomes to the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445914/ https://www.ncbi.nlm.nih.gov/pubmed/26017782 http://dx.doi.org/10.1371/journal.pone.0129214 |