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Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants
BACKGROUND: Intersubtype recombination is a powerful driving force for HIV evolution, impacting both HIV-1 diversity within an infected individual and within the global epidemic. This study examines if viral protein function/fitness is the major constraint shaping selection of recombination hotspots...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445978/ https://www.ncbi.nlm.nih.gov/pubmed/25997955 http://dx.doi.org/10.1186/s12977-015-0170-8 |