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Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants

BACKGROUND: Intersubtype recombination is a powerful driving force for HIV evolution, impacting both HIV-1 diversity within an infected individual and within the global epidemic. This study examines if viral protein function/fitness is the major constraint shaping selection of recombination hotspots...

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Detalles Bibliográficos
Autores principales:	Bagaya, Bernard S., Vega, José F., Tian, Meijuan, Nickel, Gabrielle C., Li, Yuejin, Krebs, Kendall C., Arts, Eric J., Gao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445978/ https://www.ncbi.nlm.nih.gov/pubmed/25997955 http://dx.doi.org/10.1186/s12977-015-0170-8

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